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Picture Quiz Gallery

The Lancet's interactive Picture Quiz Gallery hosts a new picture quiz each month. Play the picture quiz to test your medical knowledge and diagnostic skills. Each quiz is a multi-choice challenge which give you the option to play more or read about the patient's presentation and diagnosis.

October 2020

  1. Elsevier Ltd

    A baby with red plaques on the face

    A 3-month-old boy presented to our clinic with several well-defined erythematous and annular plaques with indurated borders located on the face appearing 3 weeks post-partum. Histological examination showed a vacuolar interface dermatitis with dermal oedema and periadnexal infiltrate of lymphocytes. What is the most likely diagnosis?
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  2. Elsevier Inc.

    Auricular inflammation with kidney injury

    A 37-year-old woman presented with a 3-year history of episodic swelling and pain in her left ear. The current episode was accompanied by decreased urine volume, hypertension, oedema of both legs, 1+ proteinuria, and microscopic haematuria. Her creatinine increased from 0.9 mg/dL 1 year ago, to 4.2 mg/dL. What is the most likely diagnosis of her kidney disease?
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  3. Elsevier Ltd

    Hemi-diaphragmatic paralysis

    Hemi-diaphragmatic paralysis can occur with compression of which of the following cervical nerve root or roots?
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  4. Elsevier Inc.

    Cold-induced acral eruptions

    A woman aged 24 years with a history of cerebral infarction presented with erythema on the fingers and toes that worsened every winter. The patient’s younger sister, mother, and maternal grandfather had similar eruptions. What is the most likely diagnosis?
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  5. Elsevier Inc.

    Muscle stiffness, instability, and liver cirrhosis

    A 44-year-old man presented with a 3-week history of an unstable gait, risus sardonicus, and subacute hypokinetic extrapyramidal symptoms. He had been diagnosed with liver cirrhosis one year earlier. L-dopa had no effect. Which diagnosis your favoured diagnosis?
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September 2020

  1. Elsevier Ltd

    An acute abdomen and café-au-lait macules

    A-25-year old male presented with acute abdominal pain and haematochezia. Multiple café-au-lait macules were seen on his body. An abdominal CT scan showed a 3 cm mass in his jejunum. Histopathologic examination diagnosed a gastrointestinal stromal tumour. What is the most likely diagnosis?
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  2. Elsevier Ltd

    Hand contractures and skin nodules in a 66-year-old woman

    A woman aged 66 years, with a history of nodal osteoarthritis, presented with cutaneous nodules and flexion contractures of her fingers. Laboratory studies yielded normal results, including inflammatory markers, serum uric acid, rheumatoid factor, cyclic citrullinated peptide antibody, antinuclear antibody, and antibodies to extractable nuclear antigens. Radiographs of the patient’s hands showed an erosive arthropathy. A biopsy from the cutaneous nodule on the left second finger showed dense dermal fibrosis, loss of elastic fibres, and immunoreactivity for smooth muscle actin characteristic of myofibroblasts. What is the most probable diagnosis?
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  3. Elsevier Inc.

    Extrahaematological manifestations of chronic myelomonocytic leukemia

    A 67-year-old man with a 2-month history of chronic myelomonocytic leukemia and bilateral facial nerve palsy, developed acute onset abdominal pain with hemodynamic instability. Which of the following is not a recognized extrahaematological problem of CMML?
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  4. Elsevier Ltd

    Starting off on the wrong foot

    A 57-year-old man presented with a slowly growing mass on the extensor surface of his left big toe. Two years earlier, a 3 cm lesion was removed from the same site. In which of the following conditions might a localised, recurrent, superficial mass be observed?
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August 2020

  1. Elsevier Inc.

    E-cigarette-induced lung disease

    The following pathologies have been described in cases of e-cigarette, or vaping, product use-associated lung injury except one, which is it?
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