SARS-CoV-2 Iota variant
Iota variant,[1] also known as lineage B.1.526, is one of the variants of SARS-CoV-2, the virus that causes COVID-19. It was first detected in New York City in November 2020. The variant has appeared with two notable mutations: the E484K spike mutation, which may help the virus evade antibodies, and the S477N mutation, which may help the virus bind more tightly to human cells.[citation needed]
By February 2021, it had spread rapidly in the New York region and accounted for about one in four viral sequences.[2][3] As of April 11, 2021[update], the variant has been detected in at least 48 U.S. states and 18 countries.[4][5]
Under the simplified naming scheme proposed by the World Health Organization, B.1.526 has been labeled Iota variant, and is considered a variant of interest (VOI), but not yet a variant of concern.[6]
Detection[edit]
The increase of the Iota variant was captured by researchers at Caltech by scanning for mutations in a database known as GISAID, a global science initiative that has documented over 700,000 genomic sequences of SARS-CoV-2.[7][8]
See also[edit]
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- SARS-CoV-2 Alpha variant
- SARS-CoV-2 Beta variant
- SARS-CoV-2 Gamma variant
- SARS-CoV-2 Delta variant
- SARS-CoV-2 Theta variant
- SARS-CoV-2 Kappa variant
- Variants of SARS-CoV-2
References[edit]
- ^ "Tracking SARS-CoV-2 variants". www.who.int. Retrieved June 1, 2021.
- ^ Rosa-Aquino, Matt Stieb, Paola (March 21, 2021). "Everything We Know About the Coronavirus Variant Spreading in New York City". Intelligencer. Retrieved April 10, 2021.
- ^ Mandavilli, Apoorva (February 24, 2021). "A New Coronavirus Variant Is Spreading in New York, Researchers Report". The New York Times. ISSN 0362-4331. Retrieved April 10, 2021.
- ^ "outbreak.info". outbreak.info. Retrieved April 10, 2021.
- ^ "PANGO lineages Lineage B.1.526". cov-lineages.org. April 22, 2021. Retrieved April 22, 2021.
- ^ "Tracking SARS-CoV-2 variants". www.who.int. Retrieved June 1, 2021.
- ^ Corum, Jonathan; Zimmer, Carl. "Coronavirus Variants and Mutations". The New York Times. ISSN 0362-4331. Retrieved April 10, 2021.
- ^ West, Anthony P.; Barnes, Christopher O.; Yang, Zhi; Bjorkman, Pamela J. (February 23, 2021). "SARS-CoV-2 lineage B.1.526 emerging in the New York region detected by software utility created to query the spike mutational landscape". bioRxiv: 2021.02.14.431043. doi:10.1101/2021.02.14.431043. PMC 8077570. PMID 33907745. S2CID 231981267.
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