COVID-19 vaccination in the United States

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COVID-19 vaccination campaign in the United States
Covid-19 Vaccination Map of USA.png
United States. Percentage with at least one vaccination dose as of June 20, 2021.[1]
DateDecember 14, 2020 (2020-12-14) – present
Location United States
Compact of Free Association:[2][3]
 Palau
 Marshall Islands
 Micronesia
CauseCOVID-19 pandemic in the United States
Organized byCenter for Disease Control and Prevention
Participants177,342,954 people have received at least one dose administered of PfizerBioNTech, Moderna and Johnson & Johnson
(June 21, 2021)
150,046,006 people have been fully vaccinated (both doses of Pfizer–BioNTech or Moderna, or one dose of Johnson & Johnson)[4]
Outcome53% of the United States population has received at least one dose of a vaccine
WebsiteCOVID-19 Vaccine: CDC

The COVID-19 vaccination campaign in the United States is an ongoing mass immunization campaign for the COVID-19 pandemic in the United States. The FDA's granted emergency use authorization of the Pfizer–BioNTech COVID-19 vaccine on December 10, 2020;[5] mass vaccinations began on December 14, 2020. The Moderna COVID-19 vaccine was granted emergency use authorization on December 17, 2020,[6] and the Johnson & Johnson COVID-19 vaccine was granted emergency use authorization on February 27, 2021.[7] At this time, there are limited data to address whether the vaccine can prevent transmission of the virus from person to person. In addition, at this time, data are not available to determine how long the vaccine will provide protection.[8]

The U.S. government initiated the campaign under the presidency of Donald Trump with Operation Warp Speed, which later transitioned to Joe Biden, who became the new President of the United States on January 20, 2021. Biden began his term with an immediate goal of a hundred million shots in his first hundred days in office, signing an executive order which included increasing supplies for vaccination.[9][10][11] This goal was met on March 19, 2021.[12] On March 25, 2021, he announced he would increase the vaccination goal to 200 million shots being given within his first 100 days in office.[13] This goal was eventually reached on April 21, 2021.[14] On May 4, 2021, Biden announced a new goal of having 70% of U.S. adults vaccinated by July 4, 2021.[15]

By April 19, 2021, all U.S. states had made Americans aged 16 and older eligible for the vaccine.[16] On May 10, 2021, the FDA approved the Pfizer vaccine for adolescents aged 12 to 15.[17]

Vaccination program[edit]

Total number of people who have received vaccinations in the United States as of June 21, 2021

  Unvaccinated population: ~155.0 million people (46.65%)
  Population who have received only one dose of a two-dose vaccine: 27,296,948[4] (8.21%)
  Population who are fully vaccinated: 150,046,006[4] (45.14%)

Vaccines administered per pharmaceutical company as of June 20, 2021

  Pfizer–BioNTech (174,521,867) (54.89%)
  Moderna (131,213,452) (41.27%)
  Johnson & Johnson (11,986,595) (3.77%)
  Not Identified (244,494) (0.08%)

Vaccines were distributed to states on a population basis, with the vaccine rollouts being administered by each individual U.S. state. The Center for Disease Control and Prevention suggested that hospital workers and nursing home personnel be the first individuals vaccinated. The subsequent phases of the rollout are determined by each individual state agency.

Eligibility of non-citizens[edit]

On February 1, 2021, the Department of Homeland Security said it "fully support[s] equal access to the COVID-19 vaccines and vaccine distribution sites for undocumented immigrants" and that related federal agencies "will not conduct enforcement operations at or near vaccine distribution sites or clinics".[18]

States may have intended that vaccines be prioritized for their residents ahead of tourists, but there was some difficulty communicating and enforcing this. Some American adults have no driver's license,[19] and the United States does not automatically provide each citizen with identity documentation in a centralized system. Furthermore, when people did not show up for their vaccine appointments, many clinics vaccinated anyone else who happened to show up so that the doses would not be wasted. As a result, some tourists as well as undocumented immigrants were vaccinated.[20]

As of early February 2021, states including Florida, California, New York and Texas were specifically trying to restrict "vaccine tourism": brief visits to the US with the primary intention of obtaining a vaccine.[21] However, contrary to rumors that spread on social media, the United States did not have a policy of cancelling visas or imposing fines on tourists who sought vaccination. Diplomats pointed out that the B1/B2 tourist visa allows people to seek medical treatment while within the United States, even if they do not turn out to be eligible for the COVID-19 vaccine.[22]

As of May 13, 2021, according to the Colombian newspaper El Tiempo, the following U.S. states were not requiring foreigners to present proof of residency to receive the vaccine: Alabama, Arizona, California, Colorado, Florida, Iowa, Louisiana, Maryland, Michigan, Minnesota, Missouri, Montana, Nevada, New Hampshire, New Mexico, New York, North Carolina, North Dakota, Ohio, Oklahoma, Pennsylvania, South Carolina, Tennessee, Texas, Virginia and Wyoming.[23] Thousands of Latin Americans were booking travel to the United States and being vaccinated in the country. Vaccination centers in some U.S. states were accepting foreign passports as valid identification. Travel agencies were advertising "vaccination tourism," and the U.S. embassy in Peru, for example, advised that travelers to the United States could seek vaccination.[24][25]

Background[edit]

From early 2020, more than seventy companies worldwide (with five or six operating primarily in the U.S.) began vaccine research.[26][27] The global competition had national security implications for various countries.[28]

In preparation for large-scale production, Congress set aside more than $3.5 billion for this purpose as part of the CARES Act.[29][27] Among the labs working on a vaccine is the Walter Reed Army Institute of Research, which has previously studied other infectious diseases, such as HIV/AIDS, ebola, and MERS. By March 18, tests had begun with dozens of volunteers in Seattle, sponsored by the U.S. government, and similar safety trials were planned for other potential vaccines.[30] Bill Gates, whose foundation shifted its focus nearly entirely to the pandemic, anticipated in early 2020 that a vaccine could be ready by early 2021.[31]

On August 5, 2020, the United States agreed to pay Johnson and Johnson more than $1 billion to create a hundred million doses of COVID-19 vaccine. The deal gave the U.S. an option to order an additional two hundred million. The doses were supposed to be provided for free to Americans if they are used in a COVID-19 vaccination campaign.[32]

Senior citizens await COVID-19 vaccine at a Maryland pharmacy in January 2021.

BIO, a trade group of all coronavirus vaccine makers except AstraZeneca, tried to persuade Secretary Azar to publish strict FDA guidelines that would help ensure the safety and public uptake of the vaccine. Politics impacted scientific practice, however, when chief of staff Mark Meadows blocked the FDA when it was realized that the timing of the provisions would make it impossible for a vaccine to be authorized before the November election.[33][34] Ultimately, the guidelines emerged[35] from the Office of Management and Budget and were published on the FDA website.[36]

As of October 2020, 44 were in clinical trials on humans, and 91 pre-clinical vaccines were being tested on animals.[37] Most of these trials are currently underway. At this time, there are limited data to address whether the vaccine can prevent transmission of the virus from person to person. In addition, at this time, data are not available to determine how long the vaccine will provide protection.[8]

On November 20, 2020, the Pfizer–BioNTech partnership submitted a request for emergency use authorization to the Food and Drug Administration (FDA),[38][39] and the FDA announced that its Vaccines and Related Biological Products Advisory Committee (VRBPAC) would review the request.[40][41] On December 11, the FDA granted emergency use authorization for the Pfizer–BioNTech vaccine.[42][43] An initial shipment of 2.9 million doses were scheduled to be distributed rapidly, and Pfizer promised to continue supplying the rest of the hundred million doses through March 2021.[44][45] Pfizer had adequate stocks available and began this distribution on December 17, 2020, but the federal government reduced the amount Pfizer was allowed to distribute.[46][47]

On December 18, 2020, the FDA granted the Moderna vaccine emergency use authorization,[48][49] which Moderna had requested on November 30, 2020.[50][51] The U.S. planned to rapidly distribute 5.9 million doses with more to come later.[52][53]

On February 27, 2021, the Johnson & Johnson COVID-19 vaccine was granted emergency use authorization by the FDA for use. However, this vaccine has faced backlash from some government officials, believing it to be not as effective as Pfizer or Moderna. On March 5, the mayor of Detroit, Mike Duggan, rejected a shipment of the Johnson & Johnson vaccine, saying, "Moderna and Pfizer are the best. And I am going to do everything I can to make sure the residents of the city of Detroit get the best."[54] After backlash, Duggan declared he would no longer decline the vaccine.[55]

On March 11, 2021, President Joe Biden announced that he would direct all states to make vaccines available to all adults no later than May 1.[56] On April 6 he said he would direct states to make all adults eligible for vaccination by April 19.[57] This deadline was met after several states opened up vaccination to everyone 16 and above the same day.[58]

As of May 2021, most experts thought the United States would be unable to achieve herd immunity, at least in the near term, given insufficient demand for the vaccine.[59] On that note, many sources are saying the new variants last longer than 14 days, such as those found at home and abroad.[60] According to an Evaluation of Available Effectiveness Data, the FDA reported on May 10, 2021: "At this time, there are limited data to address whether the vaccine can prevent transmission of the virus from person to person. In addition, at this time, data are not available to determine how long the vaccine will provide protection."[8]

Vaccines on order[edit]

Vaccine Submitted (EUA) Emergency use Authorization Deployment Submitted (Full) Full Approval
Pfizer–BioNTech Green check.svg November 20, 2020 Green check.svg December 10, 2020 Green check.svg December 14, 2020 Green check.svg May 7, 2021 Pending
Moderna Green check.svg November 30, 2020 Green check.svg December 17, 2020 Green check.svg December 21, 2020 Green check.svg June 1, 2021 Pending
Johnson & Johnson Green check.svg February 4, 2021 Green check.svg February 27, 2021 Green check.svg March 1, 2021 Dark Red x.svg No Dark Red x.svg No
Oxford–AstraZeneca N/A N/A Dark Red x.svg No Dark Red x.svg No Dark Red x.svg No
Novavax TBA (third quarter of 2021) Dark Red x.svg No Dark Red x.svg No Dark Red x.svg No Dark Red x.svg No
Sanofi–GSK Dark Red x.svg No Dark Red x.svg No Dark Red x.svg No Dark Red x.svg No Dark Red x.svg No

Vaccine distribution[edit]

Listed in millions,

As of June 21, 2021[61][62]
50
100
150
200
250
300
  •   Pfizer–BioNTech
  •   Moderna
  •   Johnson & Johnson

Vaccines in trial stage[edit]

Vaccine Type (technology) Phase I Phase II Phase III
BNT162b2 RNA Green check.svg Completed Green check.svg Completed Green check.svg Completed
mRNA-1273 RNA Green check.svg Completed Green check.svg Completed Green check.svg Completed
Ad26.COV2.S Viral vector Green check.svg Completed Green check.svg Completed Green check.svg Completed
NVX-CoV2373 Subunit Green check.svg Completed Green check.svg Completed Green check.svg Completed
AZD1222 Viral vector Green check.svg Completed Green check.svg Completed Green check.svg Completed
INO-4800 DNA Green check.svg Completed Green check.svg Completed In progress
VAT00008 Subunit Green check.svg Completed Green check.svg Completed In progress
ARCT-021 (LUNAR-COV19) RNA Green check.svg Completed In progress Dark Red x.svg Not yet
KBP-201 Subunit Green check.svg Completed In progress Dark Red x.svg Not yet
hAd5 Viral vector In progress In progress Dark Red x.svg Not yet
NDV-HXP-S Viral vector In progress In progress Dark Red x.svg Not yet
MRT5500 RNA In progress In progress Dark Red x.svg Not yet
CoV2 SAM (LNP) RNA In progress Dark Red x.svg Not yet Dark Red x.svg Not yet
MV-014-212 Live-Attenuated In progress Dark Red x.svg Not yet Dark Red x.svg Not yet
COH04S1 Viral vector In progress Dark Red x.svg Not yet Dark Red x.svg Not yet
CORVax12 DNA In progress Dark Red x.svg Not yet Dark Red x.svg Not yet
ChAdV68-S (SAM-LNP-S) Viral vector In progress Dark Red x.svg Not yet Dark Red x.svg Not yet
AdCOVID Viral vector In progress Dark Red x.svg Not yet Dark Red x.svg Not yet
VXA-CoV2-1 Viral vector In progress Dark Red x.svg Not yet Dark Red x.svg Not yet
SpFN COVID-19 vaccine Subunit In progress Dark Red x.svg Not yet Dark Red x.svg Not yet
mRNA-1283 RNA In progress Dark Red x.svg Not yet Dark Red x.svg Not yet
V590 / V591 Viral vector

History[edit]

Timeline[edit]

Timeline of daily COVID-19 vaccine doses administered in the US.[63]
Timeline of daily COVID-19 vaccine doses administered in the US.svg
See the latest date on the timeline at the bottom.
Vice President Elect Kamala Harris, like many other public officials, was vaccinated on-camera.[64][65][66]
Drive-through vaccination site at the Larkspur Ferry Terminal in Larkspur, California

December 2020[edit]

On December 14, 2020, the first doses were administered. Sandra Lindsay of Queens, New York City was the first American to be administered an FDA-emergency authorized (not FDA approved) COVID-19 vaccine.[67][68]

March 2021[edit]

On March 12, 2021, the United States surpassed 100 million doses administered.[69]

Over the course of the month, seven states (AK,[70] MS,[71] OH,[72] CT, AZ, TX,[73] and GA[74]) made the vaccine available to all adults, following a period of selective vaccination for elderly and other vulnerable populations. California and Washington announced that all adults would be eligible for a vaccine starting April 15.[75] Indiana announced that it would make vaccines available to university students and would specifically facilitate the transfer of vaccines to university-based vaccine clinics, including one such clinic at the University of Notre Dame.[76]

April 2021[edit]

On April 3, 2021, more than four million doses of the COVID-19 vaccine were reported administered in the past 24 hours, setting a new record and bringing the seven-day average to more than three million a day.[77] As of April 11, more than 187 million vaccine doses have been administered.[78] On April 13, 2021, the CDC and FDA issued a statement recommending a pause in the use of the Johnson & Johnson vaccine "out of an abundance of caution" after six women aged 18 through 48 developed a rare and severe type of blood clot called cerebral venous sinus thrombosis; on April 23, the recommended pause was lifted.[79][80][81] By April 19, 2021, all U.S. states had made Americans aged 16 and older eligible for the vaccine, meeting the deadline previously set by President Joe Biden.[16]

As of April 28, 2021, the Center for Disease Control and Prevention reported an average of 2.7 million daily vaccinations over the past week.[82]

May 2021[edit]

On May 10, 2021, the FDA granted emergency use authorization for the Pfizer vaccine for use on adolescents aged 12–15, making the United States the second country in the world, after Canada, to grant emergency use authorization for the COVID-19 vaccine for adolescents. The CDC is expected to hold a meeting to recommend how the vaccine should be used on children aged 12–15; the vaccine can be administered once CDC Director Rochelle Walensky approves the recommendation.[17] The press FDA release "Coronavirus (COVID-19) Update: FDA Authorizes Pfizer-BioNTech COVID-19 Vaccine for Emergency Use in Adolescents in Another Important Action in Fight Against Pandemic" dated May 10, 2021, reads "there are limited data to address whether the vaccine can prevent transmission of the virus from person to person. In addition, at this time, data are not available to determine how long the vaccine will provide protection."[8] Pfizer Inc. will "continue monitoring the safety of the vaccine as it is used under EUA. This plan has been updated to include the newly authorized adolescent population, and includes longer-term safety follow-up for participants enrolled in ongoing clinical trials, as well as other activities aimed at monitoring the safety of the Pfizer-BioNTech COVID-19 vaccine and ensuring that any safety concerns are identified and evaluated in a timely manner.

It is mandatory for Pfizer Inc. and vaccination providers to report the following to the Vaccine Adverse Event Reporting System for Pfizer-BioNTech COVID-19 Vaccine: all vaccine administration errors, serious adverse events, cases of Multisystem Inflammatory Syndrome and cases of COVID-19 that result in hospitalization or death."[8]

Vaccinations by state[edit]

CDC COVID-19 Vaccination Record Card.jpg
Covid-Vaccine-31 (50752381423).jpg
Covid-Vaccine-13 (50752382488).jpg
COVID-19 vaccination (2020) B.jpg
Number who have received at least one dose of a COVID-19 vaccine. Also, the percentage by state or territory.
As of June 10, 2021.[83]
State/Territory Vaccinated % of pop.
 Alabama 1,787,017 36.4
 Alaska 343,730 47.0
 Arizona 3,445,917 47.3
 Arkansas 1,218,544 40.4
 California 23,038,863 58.3
 Colorado 3,203,037 55.6
 Connecticut 2,306,716 64.7
 Delaware 544,590 55.9
 Florida 10,900,234 50.8
 Georgia 4,383,278 41.3
 Hawaii 962,100 68.0
 Idaho 685,025 38.3
 Illinois 7,170,000 56.6
 Indiana 2,870,859 42.6
 Iowa 1,579,875 50.1
 Kansas 1,387,300 47.6
 Kentucky 2,123,250 47.5
 Louisiana 1,702,116 36.6
 Maine 869,249 64.7
 Maryland 3,557,729 58.8
 Massachusetts 4,699,367 68.2
 Michigan 4,971,722 49.8
 Minnesota 3,124,967 55.4
 Mississippi 1,038,079 34.9
 Missouri 2,643,742 43.1
 Montana 495,488 46.4
 Nebraska 955,405 49.4
 Nevada 1,439,437 46.7
 New Hampshire 828,123 60.9
 New Jersey 5,504,682 62.0
 New Mexico 1,232,814 58.8
 New York 11,124,612 57.2
 North Carolina 4,621,880 44.1
 North Dakota 325,568 42.7
 Ohio 5,477,125 46.9
 Oklahoma 1,669,918 42.2
 Oregon 2,371,854 56.2
 Pennsylvania 7,691,157 60.1
 Rhode Island 659,532 62.3
 South Carolina 2,154,884 41.9
 South Dakota 433,174 49.0
 Tennessee 2,725,092 39.9
 Texas 13,224,910 45.6
 Utah 1,475,994 46.0
 Vermont 448,270 71.8
 Virginia 4,835,515 56.7
 Washington 4,437,000 58.3
 West Virginia 748,394 41.8
 Wisconsin 3,034,090 52.1
 Wyoming 219,120 37.9
50 states 168,691,344 51.5
 American Samoa 23,982 43.1
 District of Columbia 411,039 58.2
 Guam 94,357 56.9
 Northern Mariana Islands 27,247 47.9
 Puerto Rico 1,700,675 53.3
 US Virgin Islands 38,934 37.2
US territories 2,296,234 53.6
 United States 170,987,578 51.5
 Marshall Islands 16,893 28.9
 Micronesia 26,791 25.8
 Palau 13,802 77.1
Compact of Free Association 57,486 31.9
USA + CoFA 171,045,064 51.5

Public opinion[edit]

A poll conducted May 20–21, 2020, found that 44% of Republicans and 19% of Democrats believed a debunked conspiracy theory that Bill Gates was plotting to use a COVID-19 vaccine to inject microchips into the population.[84]

In early December 2020, a majority of Black and Latino Americans were at least hesitant, if not opposed, to receiving the vaccine.[85] By late February 2021, hesitancy had dropped among Black and Latino people. During the same time period, however, anti-vaccine opinions held steady among white Republicans, one-quarter of whom remained firmly opposed to getting the vaccine.[86]

A Monmouth poll conducted April 8–12, 2021, found that two-thirds of Democratic voters had already been vaccinated but only one-third of Republican voters had done so.[87] A Quinnipiac poll conducted on the same dates found that 45% of Republicans said they did not plan to be vaccinated.[88] The New York Times wrote that the vaccination program was "hitting what appears to be a soft ceiling" as it moved to dealing with the demographic groups where vaccine hesitancy was stronger.[89]

As of April 9, 2021, the vaccine was optional for U.S. Marines, and 39% of those to whom the military offered it had refused it. The highest rate of declination was at Camp Lejeune in North Carolina, where 57% of Marines had refused the vaccine.[90] As of April 22, 2021, only a third of active U.S. military service members have received COVID-19 vaccinations, with the U.S. Navy with the highest percentage of active military personnel receiving one dose at 51%, with the Marines at 36%, the Air Force/Space Force at 34%, and the Army at 27%.[91] By late May at least 58% of active military service members have received at least one dose of the COVID-19 vaccine.[92]

A Frank Luntz poll in mid-April 2021 found a rise in vaccine confidence from the previous month, despite the pause of the Johnson and Johnson vaccine. 60% of Trump voters, and 72% of Biden voters said they agreed with the statement "The bottom line is COVID-19 vaccines save lives, and Americans should continue to get vaccinated as soon as possible."[93]

According to an FDA press release dated May 10, 2021: "At this time, there are limited data to address whether the vaccine can prevent transmission of the virus from person to person. In addition, at this time, data are not available to determine how long the vaccine will provide protection."[8]

See also[edit]

Notes[edit]

References[edit]

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