COVID-19 vaccination in Japan

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COVID-19 vaccination in Japan
Date17 February 2021 (2021-02-17) – present
LocationJapan
CauseCOVID-19 pandemic in Japan
TargetFull immunisation of people in Japan against COVID-19
Participants10,387,589 people have received at least one vaccine dose
(1 June 2021)
3,610,441 have been fully vaccinated (received both vaccine doses, 1 June 2021)[1]
Suga Yoshihide, the prime minister of Japan vaccinated with COVID-19

COVID-19 vaccination in Japan is among the last major economies to begin COVID-19 vaccination.[2]

Despite a sustained COVID-19 pandemic in Japan, Japan is frequently mentioned as "slow" for vaccination after April 2021, before the upcoming 2020 Summer Olympics.[3][4]

Background[edit]

On 14 February 2021, Pfizer was approved by the government of Japan,[5] and expected rollout on 17 February 2021.[6] On 28 May 2021, Pfizer approved by the Japanese health ministry panel for the expansion of adolescents 12-15 years old.[7]

On 20 May 2021, Moderna and Astrazeneca were approved by the government of Japan.[8]

Vaccines on order[edit]

Vaccine Approval Deployment
Pfizer–BioNTech Green check.svg 14 February 2021 Green check.svg 17 February 2021
Moderna Green check.svg 20 May 2021[8] Green check.svg 23 May 2021[9]
Oxford–AstraZeneca Green check.svg 20 May 2021[8] Dark Red x.svg No

Vaccines in trial stage[edit]

Vaccine Country of origin Type (technology) Progress Ref
AG0302-COVID‑19
AnGes Inc., AMED 		Japan DNA vaccine (plasmid) Phase II–III (500)
Randomized, double-blind, placebo controlled
Nov 2020 – Apr 2021, Japan 		[10][11][12][13]
S-268019
Shionogi 		Japan Subunit Phase I–II (214)
Randomized, double-blind, placebo-controlled, parallel-group.
Dec 2020 – Jun 2022, Japan 		[14]
DS-5670
Daiichi Sankyo 		Japan RNA Phase I–II (152)
A Phase 1/2 Study to Assess the Safety, Immunogenicity and Recommended Dose of DS-5670a (COVID-19 Vaccine) in Japanese Healthy Adults and Elderly Subjects.
Mar 2021 – Jul 2022, Japan 		[15][16][17]
KD-414
KM Biologics Co 		Japan Inactivated SARS‑CoV‑2 Phase I–II (210)
Randomized, double blind, placebo control, parallel group.
Mar 2021 – Dec 2022, Japan 		[18][19]
EXG-5003
Elixirgen Therapeutics, Fujita Health University 		Japan, United States RNA Phase I–II (60)
First in Human, randomized, placebo-controlled.
Apr 2021 – Jan 2023, Japan 		[20]

History[edit]

In April 2021, prime minister Suga Yoshihide and Pfizer CEO discuss, and promise Japan will receive 50mil.[2] [21] At the time, Suga Yoshihide is tripping in the United States after meeting Joe Biden.

The roll out of the vaccines in Japan with 4 percent of the population inoculated as of May 21, 2021, and as led to criticisms on slow approval, disruptions on import and the lack of medical professionals.[22][23] A poll conducted in April showed that more than 60 percent of people were dissatisfied with Japan’s vaccine rollout, as experts say that "it is too late now to stop the spread of variants with vaccines".[24]

Distribution issues[edit]

2020 Summer Olympics[edit]

See also: 2020 Summer Olympics § Biosecurity protocols

References[edit]

  1. ^ "Ongoing Topics - Novel Coronavirus Vaccines". Prime Minister of Japan and His Cabinet. 28 May 2021. Retrieved 2 June 2021.
  2. ^ a b Kanishka Singh (2021-04-18). "UPDATE 1-Japanese PM, Pfizer CEO discuss delivery of additional vaccine doses in 2021 to Japan". Retrieved 2021-05-25.
  3. ^ "Japan's slow vaccination process as Tokyo 2020 looms". CNN. April 26, 2021. Retrieved 2021-05-25.
  4. ^ Blake Essig, Emiko Jozuka and Ben Westcott (April 14, 2021). "With 100 days until the Tokyo Olympics, Japan has vaccinated less than 1% of its population. That's a problem". CNN. Retrieved 2021-05-25.
  5. ^ "Japan approves Pfizer's COVID-19 vaccine, 1st for domestic use". Nikkei Asia. 14 February 2021. Retrieved 14 February 2021.
  6. ^ "Japan gives first COVID-19 vaccinations to Tokyo health workers". The Japan Times. 17 February 2021. Retrieved 31 May 2021.
  7. ^ "Japan to approve Pfizer COVID-19 vaccine for 12- to 15-year-olds". Kyodo News. 28 May 2021. Retrieved 31 May 2021.
  8. ^ a b c "日本批准使用莫德納、AZ疫苗". The Liberty Times. 2021-05-05.
  9. ^ "自衛隊員にモデルナ製ワクチン　国内初、大規模接種会場を運営". Tokyo Shimbun. 23 May 2021. Retrieved 2 June 2021.
  10. ^ "About AnGes – Introduction". AnGes, Inc. Archived from the original on 11 October 2020. Retrieved 1 August 2020.
  11. ^ "Study of COVID-19 DNA Vaccine (AG0301-COVID19)". ClinicalTrials.gov. United States National Library of Medicine. 9 July 2020. NCT04463472. Archived from the original on 11 October 2020. Retrieved 14 July 2020.
  12. ^ "Study of COVID-19 DNA Vaccine (AG0302-COVID19)". clinicaltrials.gov. United States National Library of Medicine. Retrieved 11 March 2021.
  13. ^ "Phase II / III Study of COVID-19 DNA Vaccine (AG0302-COVID19)". clinicaltrials.gov. United States National Library of Medicine. Retrieved 11 March 2021.
  14. ^ "Safety and Immunogenicity of an Intranasal RSV Vaccine Expressing SARS-CoV-2 Spike Protein (COVID-19 Vaccine) in Adults". jrct.niph.go.jp. Japan Registry of Clinical Trials. Retrieved 21 March 2021.
  15. ^ "Daiichi Sankyo Initiates Phase 1/2 Clinical Trial for mRNA COVID-19 vaccine in Japan" (PDF) (Press release). Daiichi Sankyo. Retrieved 17 April 2021.
  16. ^ "Daiichi takes mRNA COVID-19 vaccine into clinic as Japanese R&D belatedly fires up". Fierce Biotech. March 22, 2021. Retrieved 12 April 2021.
  17. ^ "Study of DS-5670a (COVID-19 Vaccine) in Japanese Healthy Adults and Elderly Subjects". clinicaltrials.gov. United States National Library of Medicine. Retrieved 12 April 2021.
  18. ^ "Japan's KM Biologics begins clinical trial of COVID-19 vaccine candidate". Reuters. 22 March 2021.
  19. ^ "20歳以上65歳未満の健康成人、及び65歳以上の健康な高齢者を対象に、COVID-19に対するワクチン（KD-414）の安全性及び免疫原性を検討するための、プラセボを対照とする多施設共同二重盲検ランダム化並行群間比較試験". jrct.niph.go.jp. Japan Registry of Clinical Trials. Retrieved 7 May 2021.
  20. ^ "Safety and Immunogenicity of EXG-5003". clinicaltrials.gov. United States National Library of Medicine. Retrieved 2 May 2021.
  21. ^ "Japan to receive 50 mil. additional doses of Pfizer vaccine". April 21, 2021. Retrieved 2021-05-25.
  22. ^ Kosaka, Makoto; Hashimoto, Takanao; Ozaki, Akihiko; Tanimoto, Tetsuya; Kami, Masahiro (2021-06-02). "Delayed COVID-19 vaccine roll-out in Japan". The Lancet. 0 (0). doi:10.1016/S0140-6736(21)01220-4. ISSN 0140-6736. PMC 8172150. PMID 34089658.
  23. ^ "EXPLAINER: Why Japan has been slow to roll out vaccinations". The Asahi Shimbun. Retrieved 2021-06-08.
  24. ^ McCurry, Justin (26 April 2021). "Japan's slow Covid vaccine rollout casts cloud over Olympics". The Guardian. Retrieved 8 June 2021.
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