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COVID-19 vaccination in India

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COVID-19 vaccination programme
India Vaccination Map.jpg
Per capita fully vaccination map as of 22 January 2022
Date16 January 2021 (2021-01-16) – present
(1 year, 24 days ago)
LocationIndia India
CauseCOVID-19 pandemic in India
TargetImmunisation of Indians against COVID-19
Budget35,000 crore (US$4.6 billion)[1]
Organised byGovernment of India
Indian Council of Medical Research
State governments of India
Participants
  • 95,21,64,965 people with one dose administered of Covaxin or Oxford–AstraZeneca vaccine or Sputnik V
  • 74,08,25,503 people have been fully vaccinated with both doses of Covaxin or Oxford–AstraZeneca vaccine or Sputnik V
  • 1,57,16,237 people have been administered Precautionary/Booster doses of Covaxin or Oxford–AstraZeneca vaccine or Sputnik V
Outcome
  • 69% of the Indian population has received one dose.
  • 53% of the Indian population has received both doses
Websitewww.mohfw.gov.in,
www.cowin.gov.in
As on 09th February 2022 (07:00AM)

India began administration of COVID-19 vaccines on 19 January 2021. As of 9 February 2022, India has administered over 1.71 billion doses overall, including first, second and precautionary (booster) doses of the currently approved vaccines.[2][3] In India, 94% of the eligible population (15+) has received at least one shot, and 73% of the eligible population (15+) is fully vaccinated.[4]

India initially approved the Oxford–AstraZeneca vaccine (manufactured under license by Serum Institute of India under the trade name Covishield) and Covaxin (a vaccine developed locally by Bharat Biotech). They have since been joined by the Sputnik V (manufactured under license by Dr. Reddy's Laboratories, with additional production from Serum Institute of India being started in September[5][6]), Moderna vaccines, Johnson & Johnson vaccine and ZyCoV-D (a vaccine locally developed by Zydus Cadila)[a][b] and other vaccine candidates undergoing local clinical trials.

Vaccination programme

Cumulative doses administered across the country

Total doses administered across the country as of February 9, 2022 [7][8]

Dose Vaccination (Percentage of eligible population vaccinated)
Partially Vaccinated
952,164,965(93.99)
Fully Vaccinated
740,825,503(73.13)
Precautionary(Booster) Dose
15,716,237

Monthly graph of cumulative doses administered across the country

Graph of daily doses administered across the country

Graph of daily doses administered. Last updated: February 9, 2022[9]

   Daily vaccinations (1st dose only)    Daily vaccinations (2nd dose only)

Vaccine administration by Gender

Vaccinations in India by Gender as of February 9, 2022[7][8]

Gender Vaccination
Male 86,34,39,874
Female 82,51,19,187
Others 4,04,978

Vaccine administration by vaccine brand

Vaccinations in India by Vaccine Brand as of February 9, 2022 [7][8]

Brand Vaccination
Covishield 1,44,84,28,346
Covaxin 25,43,83,387
Sputnik V 12,11,649

Vaccine administration by age group

Vaccinations in India by Age Group as of February 9, 2022 [7][8]

Age Group Vaccination
15-17 5,99,63,874
18-44 1,01,00,90,652
45-60 39,08,29,364
60+ 39,08,29,364

States by Vaccine Coverage

Note icon.svg (as of 15 September (7:00 IST))

Number of Vaccination Centres

Sites conducting vaccination in India
Emojione BW 1F3E5.svgVaccine - The Noun Project.svg

Total-1,12,500
Government[fn 1] — 1,10,000
Private[fn 2] — 2,500

Source: CoWin Dashboard[10]

Note icon.svg As of 2 February (9:38 PM IST)
OOjs UI icon alert-warning.svg This data is subject to change anytime.

Citizens above the age of 15 can book appointments through the COWIN platform or can do a Walk-In registration on site. All vaccine centres have registration desks, vaccine booths and observation rooms. Vaccine certificates can be downloaded digitally through the COWIN platform, or citizens can ask for a hard copy from vaccination centres. All government run vaccination centers provide free of cost vaccines, private centers do charge.[11]

Background and timeline

A vaccination centre in Delhi.
India's COVID-19 vaccination deployment till 3 June

First Phase, initial approvals, launch of vaccination programme

In September 2020, India's Health minister Harsh Vardhan stated that the country planned to approve and begin distribution of a vaccine by the first quarter of 2021.[12] The first recipients were to be 30 million health workers directly dealing with COVID patients.[13]

A vial of Covishield, the Indian-manufactured version of the AstraZeneca vaccine.
A vial of Covaxin
Vaccination drive for COVID prevention in Bhopal, India

On 1 January 2021, the Drug Controller General of India (DCGI) approved emergency use of the Oxford–AstraZeneca vaccine (local trade name "Covishield").[14][15][16] On 2 January, the DCGI also granted an interim emergency use authorisation to BBV152 (trade name "Covaxin"), a domestic vaccine developed by Bharat Biotech in association with the Indian Council of Medical Research and National Institute of Virology.[17] This approval was met with some concern, as the vaccine had not then completed phase 3 clinical trials.[18] Due to this status, those receiving Covaxin were required to sign a consent form,[19] while some states chose to relegate Covaxin to a "buffer stock" and primarily distribute Covishield.[20]

COVID-19 vaccination roll out in AIIMS, New Delhi, India on 16 January 2021

India began its vaccination programme on 16 January 2021, operating 3,006 vaccination centres on the onset.[21] Each vaccination centre will offer either Covishield or Covaxin, but not both.[22] 165,714 people were vaccinated on the first day of availability. Difficulties in uploading beneficiary lists at some sites caused delays.[23] In the first three days, 631,417 people were vaccinated. Of these, 0.18% reported side-effects and nine people (0.002%) were admitted to hospitals for observation and treatment.[24][25] Within those first days, there were concerns about low turnout, due to a combination of vaccine safety concerns, technical problems with the software used, and misinformation.[26]

The first phase of the rollout involved health workers and frontline workers, including police, paramilitary forces, sanitation workers, and disaster management volunteers.[21] By 1 March, only 14 million healthcare and frontline workers had been vaccinated, falling short of the original goal of 30 million.[27]

Second phase

The next phase of the vaccine rollout covered all residents over the age of 60, residents between the ages of 45 and 60 with one or more qualifying comorbidities, and any health care or frontline worker that did not receive a dose during phase 1. Online registration began on 1 March via the Aarogya Setu app and Co-WIN ("Winning over COVID-19") website.[28][29][30] Amid the beginnings of a major second wave of infections in the country,[31][32][33] vaccine exports were suspended in March 2021, and the government ordered 110 million Covishield doses from SII.[34] The company aims to produce 100 million doses per month, but by May 2021 its production capacity was only 60–70 million doses.[35][36] Following the conclusion of its trial, the DCGI issued a standard emergency use authorisation to Covaxin on 11 March 2021.[37]

From 1 April, eligibility was extended to all residents over the age of 45.[38] On 8 April, Prime Minister Narendra Modi called for a four-day Teeka Utsav ("Vaccine Festival") from 11 to 14 April, with a goal to increase the pace of the program by vaccinating as many eligible residents as possible. By the end of the Utsav, India had reached a total of over 111 million vaccine doses to-date.[39][40][41]

Third phase, Sputnik V approval

On 12 April, the DCGI approved Russia's Sputnik V vaccine for emergency use in India. A phase 3 trial was conducted in the country in September 2020, which showed 91.6% efficacy.[42] The local distributor Dr. Reddy's Laboratories stated that it planned to have the vaccine in India by late May 2021.[43]

On 19 April, it was announced that the next phase of the vaccination programme would begin on 1 May, extending eligibility to all residents over the age of 18. Under phase 3, individual stakeholders were also given more flexibility in how they conduct the vaccination programme. As part of this plan, only half of the vaccines procured by the Central Drugs Laboratory from manufacturers would be distributed by the central government. This supply would go to government-run clinics and be offered free-of-charge to residents 45 and over and priority workers and siphoned off to states based on factors such as the number of active cases and how quickly they are administering vaccines. The remainder would be offered to individual states and purchased on the open market (including private hospitals), which would be able to serve residents over the age of 18.[44][45][46]

Registration for the next phase began on 28 April; a single-day record of nearly 13.3 million people registered.[47] Due to supply issues, several states, including Delhi, Gujarat and Madhya Pradesh announced that they would delay their wider rollouts of vaccines to later in the month.[48]

The initial shipment of 150,000 Sputnik V doses arrived on 1 May, and began to be administered on 14 May.[49][50][51] An estimated 156 million doses is expected between August and December; initially, doses will be sourced from Russia, but domestic production is expected to begin by August 2021.[52][53][54]

On 13 May, the DCGI approved phase 2 and phase 3 trials of Covaxin on children 2–18.[55] On 14 May, health officials projected that based on the anticipated approval of additional vaccine options, it could receive at least 2.17 billion more vaccine doses from August to December 2021.[56][57] On 25 May, India exceeded 200 million vaccine doses administered in total.[58] On 3 June, the Ministry of Health and Family Welfare pre-ordered 300 million doses of a potential fourth vaccine, Corbevax, which is undergoing phase 3 clinical trials.[59]

On 23 May, the union government allowed walk-in registrations for vaccination throughout the country; a health worker at the vaccination centre would register the recipient in the Co-win vaccination database. The government claimed in an affidavit to the Supreme Court that as of June 23 about 78 per cent of vaccines had been administered via walk-in registration.[60]

Return to centralised procurement

On 31 May, an affidavit was issued in the Supreme Court of India requesting a review of the central government's vaccine distribution strategy, suggesting that the decision to only offer doses at no charge to priority workers and residents over the age of 45 was "prima facie arbitrary and irrational".[61]

On 7 June, Prime Minister Modi announced that India would migrate back to centralised procurement of vaccines by 21 June. In an address, Modi stated that multiple chief ministers had requested that the central government reconsider its new distribution strategy and reinstate the system it had used before May. As before, the centre will procure up to 75% of the country's vaccine supplies from manufacturers in bulk and distribute them to states at no additional charge. Vaccines would now be offered at no charge for those in the 18–44 age group. Private hospitals will still be responsible for the remaining 25% of procurement, but fees for appointments are now capped at 150 (US$2.00).[62][63]

On 21 June, the day these changes took effect, approximately 8,270,000 doses were administered—India's largest single-day total till that point. The states of Madhya Pradesh and Karnataka had the highest local totals.[64][65][66] Member of Parliament, Rajya Sabha P. Chidambaram accused Bharatiya Janata Party of having "hoarded" vaccine doses in the days leading up to 21 June in order to encourage larger numbers; seven states controlled by the BJP were among the top ten states to have administered vaccine doses that day, few of these states had below-average vaccination numbers in the days leading up to 21 June (such as Madhya Pradesh, which went from 692 doses on 20 June to 1,690,000 the next day, and numbers had dropped significantly in the state the next day).[67][68][69][70]

On 23 June, India surpassed over 300 million vaccine doses administered in total.[71] On 28 June, India overtook the United States in total vaccine doses administered.[72] On 29 June, the DCGI approved the Moderna vaccine (which is being imported by Cipla) for emergency use. Vinod Kumar Paul stated that the Pfizer vaccine was also likely to be approved soon.[73][74]

500 million mark, Johnson & Johnson Covid-19 vaccine approval and record

On 6 August 2021, India crossed the 500 million doses milestone within 6 months from the onset of the vaccination program.[75]

On 7 August 2021, the Drug Controller General of India (DCGI) approved emergency use of the Johnson and Johnson single-dose vaccine.[76] On 16 Aug 2021, India administered around 8.81 million doses of COVID-19 vaccines, achieving the highest single-day record and overtaking its own previous record of 8.61 million doses, by 16 August the cumulative doses had surpassed the 55 millon mark.[77][78]

ZyCoV-D approval for ages 12 & above and single day vaccination records

On 20 August 2021, India granted emergency use approval to the world's first DNA based COVID-19 vaccine, ZyCoV-D manufactured by Zydus Cadila for adults and children aged 12 years and above. The vaccine is administered using a needle-free applicator.[79][80] The government announced on 30 September 2021 that the ZyCoV-D vaccine will be a three dose vaccine and it will be included in the Covid vaccination programme of India.[81]

Since August 10, 2021, foreign nationals residing in India can now receive the COVID-19 vaccine by registering themselves on the Cowin platform; like other eligible beneficiaries, the foreign nationals can book a slot via the portal and use their passport as a document to verify their identity for the registration process.[82]

By 26 August 2021, 50% of the adult population in India were inoculated with at least one dose of the approved vaccines, which included 99% coverage among healthcare workers and 100% front-line workers for the first dose.[83]

On 27 August 2021, India crossed the milestone of administering more than 10 million (1 crore) doses of COVID-19 vaccine in a single day, setting a new world record. Uttar Pradesh topped the list with 2.8 million doses, followed by Karnataka with 1 million doses and Maharashtra at third with 0.98 million doses.[84]

On 29 August 2021, Himachal Pradesh became the first state to complete administering first doses of COVID-19 vaccines to 100% of the population.[85] On 31 August, India again set another single-day vaccination record by inoculating around 12 million (1.2 Crore) doses in 24 hours.[86]

By September 2021, all adult people in Sikkim, Dadra and Nagar Haveli, Himachal Pradesh, Goa, Ladakh, and Lakshadweep have received at least one dose of Covid vaccine as the cumulative jabs administered in the country crossed 75 crores. Many city corporations, talukas, gram panchayats and districts had also administered the first dose of COVID-19 vaccination to 100 per cent of their adult population.[87][88] [89]

As many as 25 million people were vaccinated on Narendra Modi's birthday on the 17th of September 2021. This is the highest single-day vaccination tally so far in the whole world.[90] There are allegations that a lot of pressure could have been put on officials to increase and twist to record vaccination numbers on the Prime Minister's birthday as some people who had not received their Covid shots somehow seem to have been issued vaccination certificates including those who are deceased.[91][92]

On 27 September, India administered over 1 crore vaccine doses for the fifth time, and total vaccination coverage crossed 86 crore (860 million).[93]

On 2 October, Union health minister Mansukh Mandaviya announced that India crossed the landmark of administrating 90 crore vaccine doses.[94]

1 billion mark, vaccine clinical trial for children aged 7-11 and government's view on booster shots

The Government and India's drug regulator allowed vaccine manufacturer, Serum Institute on 28 September 2021 to enroll children between seven and 11 years of age for its COVID-19 vaccine trial.[95]

The conversation around the booster doses of COVID-19 vaccines gained momentum after people in many western countries were inoculated with the booster dose, or the third dose. The debate is raging in India where a major chunk of the eligible population has already been inoculated with at least one dose since the beginning of the Covid vaccination drive in January. The Indian government has, by far, maintained that booster shots of Covid vaccines and the benefit they provide are under purview and study, the current focus should be on ensuring two doses for every adult in the country.[96]

On 21 October 2021, India crossed the one billion mark for administered doses.[97]

Booster dose and vaccination for youths

India will start giving booster shots from January 10 2022 to health and frontline workers and those over 60 with comorbidities or other health problems -Prime Minister Narendra Modi announced. He also said vaccinations will begin for youths between 15 and 18 years from January 3 2022.[98] Among healthcare and frontline workers and those aged 60 and above with comorbidities, prioritisation and sequencing would be based on completion of nine months or 39 weeks from the date of the second dose as of January 10, the government said in its guidelines. Youths between 15 and 18 years can register online on CoWin from January 1 2022 or onsite at vaccination centres from January 3 2022. Covaxin is the only covid vaccine available for citizens between 15 and 18. [99]

Vaccine development and distribution

Prime Minister Narendra Modi visiting the Serum Institute of India on 28 November 2020.

As of early May 2020, there were over 30 vaccine candidates in development in India, many of which were already in pre-clinical trials.[100]

The Pune-based Serum Institute of India (SII) is the world's largest vaccine maker. This existing capacity enabled India to be a major participant in the COVAX programme to distribute vaccines to developing countries.[101] In February 2020, SII had begun animal trials of vaccine candidates.[102] SII announced in April 2020 that it would apply for clinical trials from the Drug Controller General of India (DCGI) in April 2020. SII president Adar Poonawalla said that a vaccine would be delivered within a year, but projected an efficacy between 70 and 80%.[103]

In August 2020, SII received approvals for phase 2 and phase 3 trials of its version of a vaccine being developed by AstraZeneca and the University of Oxford's Vaccitech.[104] SII joined GAVI in a partnership with the Bill & Melinda Gates Foundation to produce 100 million doses of vaccine for developing countries.[105] The SII planned to manufacture 1.5 and 2.5 billion doses of the AstraZeneca vaccine per-year under the trade name "Covishield".[106] By its approval in January 2021, the company had stockpiled 50 million doses, but well short of its own target of 400 million.[107][108] The government ordered 21 million doses to be delivered by February, but the company said no indication of any further orders were given.[34] The company began to export the remaining stocks instead.[106]

Hyderabad-based Bharat Biotech, in collaboration with U.S.-based FluGen, expected to begin the first clinical trials of a nasal vaccine by late-2020.[109] The Indian Council of Medical Research partnered with Bharat Biotech in May 2020 to develop a COVID vaccine entirely within India.[110] In June 2020, it received DCGI approval to begin phase 1 and phase 2 trials on its vaccine, BBV152 (trade name "Covaxin").[111] In September 2020, it was reported that in pre-clinical trials on animals, Covaxin was able to build immunity.[112] In July 2021, Bharat Biotech reported the vaccine to be 64% (95% CI, 2982%) effective against asymptomatic cases, 78% (6586%) effective against symptomatic cases, 93% (57100%) effective against severe COVID-19 infection, and 65% (3383%) effective against the Delta variant.[113][114] On 20 April 2021, Bharat Biotech announced that it had expanded its production capabilities for Covaxin to 700 million doses per-year.[115]

Cadila Healthcare began vaccine development in March 2020, including a viral vector vaccine and a DNA plasmid vaccine.[116][117] In mid-July 2020, Cadila held early human trials of its vaccine candidate ZyCoV-D,[118] and received approval for phase 3 trials in January 2021.[119][120] It began large-scale production in April 2021, with Cadila expecting to receive emergency authorisation between May and June 2021.[121] On 1 July 2021, Cadila Healthcare reported the efficacy to be 66.6% against symptomatic COVID-19 and 100% against moderate or severe disease in its interim analysis of its phase 3 trial data.[122][123]

In September 2020, Dr. Reddy's partnered with the Russian Direct Investment Fund (RDIF) to conduct phase 3 trials of the Sputnik V vaccine in India, and to distribute the vaccine there once approved.[124][125] In April 2021, RDIF CEO Kirill Dmitriev told NDTV that they had "five great manufacturers in India" who would be producing the vaccine, and felt that the country could become Sputnik V's "production hub" for use and export.[126] Dr. Reddy's is also working with the RDIF on approval of "Sputnik Light"—a regiment of Sputnik V consisting only of the first dose.[54]

In April 2021, phase 3 clinical trials were approved for another vaccine, Corbevax, a protein subunit that is being developed by BioE, the Baylor College of Medicine, and Dynavax Technologies.[59][127]

On 2 June 2021, the DCGI removed the requirement that India-specific clinical trials (bridging trials) be held for vaccine candidates developed outside of India, provided that they are already approved by a recognised international public health agency such as the World Health Organization (WHO), European Medicines Agency (EMA), US Food and Drug Administration (FDA), UK Medicines and Healthcare products Regulatory Agency (MHRA), or Japan's Pharmaceuticals and Medical Devices Agency. These changes were intended to help expedite the availability of vaccines already in use in other countries.[73][128]

In mid-July, it was reported that approval of the Moderna and Pfizer vaccines, as well as a shipment of vaccines donated by the United States (which includes the AstraZeneca, Janssen, Moderna, and Pfizer vaccines), had faced delays due to requests from their manufacturers for indemnity clauses from Indian authorities, which would relieve them from legal liability for adverse reactions.[129][130]

On 21 September 2021, the Indian Government said that it will not purchase the Pfizer-BioNTech and Moderna vaccines as domestic output of more affordable and easier-to-store vaccines has jumped.[131]

In the Quad summit, Prime Minister Narendra Modi announced that India would make 8 million doses of J&J vaccine available by the end of October under the Quad vaccine partnership. It will be manufactured in India by the Biological E. This would be ready by the end of October, compatible with our decision to resume vaccine export.[132]

On 6th February 2022, DCGI approved sputnik light covid vaccine for emergency use in India.[133]

Vaccine deployment strategies

Optimizing vaccination deployment for India[134] includes tailoring of strategies to the demographic and epidemiologic situation by modeling vaccination scenarios,[135] explore measures to reach children at risk[136] and co-optimizing vaccination strategy for societal and individual benefit in parallel.[137]

Vaccine on order

Vaccine Status Production Capacity Planned Capacity Doses ordered Approval Deployment
Covishield Green check.svg In use 840 million [138] - 750 million [139][140] Green check.svg 01 January 2021[141] Green check.svg 16 January 2021[142]
Covaxin Green check.svg In use 700 million [143] - 550 million [139] Green check.svg 03 January 2021[144] Green check.svg 16 January 2021[142]
Sputnik V Green check.svg In use 140 million - 156 million [145][139] Green check.svg 12 April 2021[42] Green check.svg 14 May 2021[146]
Moderna Green check.svg Approved Import only[147] - - Green check.svg 29 June 2021[148] Dark Red x.svg Order Cancelled[149]
Johnson & Johnson Green check.svg Approved - 8 million[132] - Green check.svg 7 Aug 2021 [150] Deliveries expected from October 2021[132]
ZyCoV-D Green check.svg Approved - 240 million [151] 50 million [139] Green check.svg 20 August 2021[152] Deliveries expected from October 2021
Corbevax Green check.svg Approved - 960 million [153] 300 million [154] Green check.svg 28 December 2021[155] Dark Red x.svg Not yet
Covovax Green check.svg Approved - - 200 million [139] Green check.svg 28 December 2021[155] Dark Red x.svg Not yet
Sputnik Light Green check.svg Approved - - - Green check.svg 6 February 2022[156] Dark Red x.svg Not yet

In September 2021, India's government announced that it would not buy COVID-19 shots from Pfizer (PFE.N)/BioNTech (22UAy.DE) and Moderna (MRNA.O), mainly because the domestic output of more affordable and easier-to-store vaccines of Serum Institute of India, Bharat Biotech & Cadila Healthcare has jumped. India will make 8 million doses of the Johnson and Johnson vaccine available by the end of October under the Quad vaccine partnership.[132]

Vaccines in trial stage

Vaccine Type (technology) Phase I Phase II Phase III No. of Participants in Clinical Trial Planned Capacity
BBV154 Adenovirus vector (intranasal) Green check.svg Completed In progress Pending 175[157][158] 100 million[139]
HGC019 mRNA Green check.svg Completed In progress Pending 120 [159] 60 million [139]

Vaccine Maitri

Vaccine Maitri (English: Vaccine Friendship)[160] is a humanitarian initiative undertaken by the Indian government to provide COVID-19 vaccines to countries around the world.[161] The government started providing vaccines from 20 January 2021. As of 9 May 2021, India had delivered around 66.3 million doses of vaccines to 95 countries.[162] Of these, 10.7 million doses were gifted to 47 countries by the Government of India. The remaining 54 million were supplied by the Serum Institute of India under its commercial and COVAX obligations. In late March 2021, the Government of India temporarily froze exports of the Covishield, citing India's own COVID crisis and the domestic need for these vaccines.[163] The Health Minister of India, Mr. Mansukh Mandaviya announced in September that India will resume the export of vaccines from October to the rest of the world.[164][165]

Oxford AstraZeneca COVID-19 vaccine (Indian version) 2021 L.jpeg
Countries that received doses of the Indian-made Covaxin as of 6 March 2021

200,000 doses of COVID-19 vaccines were gifted by India to the UN peacekeepers on 27 March to be distributed to all peacekeeping missions.[166]

Vaccines

India has two approved COVID-19 vaccines: Covishield and Covaxin. Both of them were exported and used in foreign grants by the Government of India.

Covishield

A vial of Covishield, the Indian-manufactured version of the AstraZeneca vaccine.

On 1 January 2021, the Drug Controller General of India, approved the emergency or conditional use of Covishield.[167] Covishield is developed by the University of Oxford and its spin-out company, Vaccitech.[168]

Covaxin

A vial of Covaxin,India's first indigenous COVID-19 vaccine by Bharat Biotech

On 2 January 2021, Covaxin India's first COVID-19 vaccine, developed by Bharat Biotech in association with the Indian Council of Medical Research and National Institute of Virology received approval from the Drug Controller General of India for its emergency or conditional usage.[169]

Vaccine supply

India kicked off international shipment of the vaccines on 20 January 2021, only four days after starting its own vaccination program.[170] Bhutan and Maldives were the first countries to receive vaccines as a grant by India. This was quickly followed by shipments to Nepal, Bangladesh, Myanmar and Seychelles.[170] By mid-March 2021, India was also supplying vaccines on a commercial basis to countries including Canada,[171] the UK,[172] and Saudi Arabia.[173]

As of 28 January, 2022, India had exported total 14,63,48,400 doses including 1,42,67,000 vaccine provided as grant to more than 96 nations.[162]

The Serum Institute of India was selected as a key supplier of cost-effective COVID-19 vaccines to the COVAX initiative,[174] 19.8 million doses of Covishield vaccines were supplied by India to various countries through the initiative.[175] In May, when COVAX was already short 140 million doses,[176] the Serum Institute announced that it expected to maintain its suspension of vaccine deliveries to COVAX through the end of 2021[177] due to the second wave of COVID-19 in India[178] and the US ban on export of key raw materials.[179]

International reaction

International organizations

  • IMF: IMF chief economist Gita Gopinath lauded India for playing a key role during the crisis by dispatching vaccines to many countries. She said "I also want to mention that India really stands out in terms of its vaccine policy. If you look at where exactly is one manufacturing hub for vaccines in the world – that will be India."[180]

Countries

  •  Jamaica[181] of the OACPS has thanked Indian efforts in delivering vaccines to developing and least developed countries.
  •    Nepal Prime minister Khadga Prasad Oli thanked India stating; “We got an early chance to administer the Covid-19 vaccine. For this, I thank our neighbouring nation India, its government, the people, and especially Prime Minister Narendra Modi. They sent 10 lakh doses of vaccines to us as a grant within a week of the roll-out in India.”[182]
  •  St. Lucia on behalf of CARICOM thanked India for providing vaccine supplies to them.[181][183]
  •  Barbados Prime Minister Mia Amor Mottley thanked Prime Minister Narendra Modi for the supply of "Made in India" COVID-19 vaccines. She tweeted, "PM Modi made it possible for more than 40,000 persons in Barbados and tens of thousands elsewhere, to receive their 1st dose of COVISHIELD via Vaccine Maitri before receiving his. A genuine demonstration of generosity. Thank you and we wish you continued good health."[184]
  •  Antigua and Barbuda Prime Minister Gaston Browne had thanked Prime Minister of India Narendra Modi "for demonstrating an act of benevolence, kindness and empathy", for sending vaccines to Caribbean countries.[185]
  •  Afghanistan Afghanistan's ambassador to India Farid Mamundzay said "Thank you, India for providing Afghan people lifesaving gift on the first day of 2022!"[186]

Leaders who received vaccines provided by India

Gallery

Vaccination rollout statistics by State or UT

State/union territory Population (2021 census projection) 1st dose 2nd dose Precautionary/ Booster Dose Cumulative doses administered Percentage of people given one dose Percentage of people fully vaccinated
India 1,38,94,19,783 95,21,64,965 74,08,25,503 1,57,16,237 1,70,87,06,705 69% 53%
Andaman and Nicobar Islands 4,00,000 3,27,758 3,14,694 6,763 6,49,215 82% 79%
Andhra Pradesh 5,27,87,000 4,29,52,885 3,83,95,430 10,98,557 8,24,46,872 81% 73%
Arunachal Pradesh 15,33,000 8,80,680 6,93,183 19,639 15,93,502 57% 45%
Assam 3,50,43,000 2,32,47,055 1,86,22,700 1,99,182 4,20,68,937 66% 53%
Bihar 12,30,83,000 6,51,93,171 4,90,80,295 6,03,421 11,48,76,887 53% 40%
Chandigarh 12,08,000 11,17,016 8,61,180 19,877 19,98,073 92% 71%
Chhattisgarh 2,94,93,000 1,94,50,111 1,52,45,934 3,00,198 3,49,96,243 66% 52%
Dadra and Nagar Haveli 6,08,000 4,42,584 3,27,523 2,633 7,72,740 73% 54%
Daman and Diu 4,09,000 3,09,503 2,60,747 3,847 5,74,097 76% 64%
Delhi 2,05,71,000 1,71,22,993 1,27,29,180 3,35,226 3,01,87,399 83% 62%
Goa 15,59,000 13,87,360 12,04,966 25,554 26,17,880 89% 77%
Gujarat 6,97,88,000 5,15,76,171 4,70,06,311 16,36,741 10,02,19,223 74% 67%
Haryana 2,94,83,000 2,26,49,226 1,71,39,203 1,82,077 3,99,70,506 77% 58%
Himachal Pradesh 73,94,000 62,99,521 57,95,899 1,23,252 1,22,18,672 85% 78%
Jammu and Kashmir 1,34,08,000 1,06,03,691 1,00,67,083 2,21,577 2,08,92,351 79% 75%
Jharkhand 3,84,71,000 2,18,12,371 1,33,65,422 1,77,580 3,53,55,373 57% 35%
Karnataka 6,68,45,000 5,18,99,858 4,48,48,402 9,26,625 9,76,74,885 78% 67%
Kerala 3,54,89,000 2,79,81,520 2,28,57,574 7,49,939 5,15,89,033 79% 64%
Ladakh 2,97,000 2,26,308 1,82,954 22,415 4,31,677 76% 62%
Lakshadweep 68,000 59,420 54,976 2,093 1,16,489 87% 81%
Madhya Pradesh 8,45,16,000 5,76,66,261 5,29,25,670 7,86,884 11,13,78,815 68% 63%
Maharashtra 12,44,37,000 8,66,83,163 6,28,41,573 11,58,055 15,06,82,791 70% 51%
Manipur 31,65,000 14,69,735 10,85,666 43,228 25,98,629 46% 34%
Meghalaya 32,88,000 13,46,152 9,40,789 22,089 23,09,030 41% 29%
Mizoram 12,16,000 8,14,511 6,19,872 21,087 14,55,470 67% 51%
Nagaland 21,92,000 8,54,949 6,18,046 15,639 14,88,634 39% 28%
Odisha 4,56,96,000 3,23,25,376 2,55,77,476 6,62,206 5,85,65,058 71% 56%
Puducherry 15,71,000 9,25,140 6,14,880 10,077 15,50,097 59% 39%
Punjab 3,03,39,000 2,10,16,976 1,46,70,152 2,95,972 3,59,83,100 69% 48%
Rajasthan 7,92,81,000 5,30,52,773 4,14,44,872 10,53,577 9,55,51,222 67% 52%
Sikkim 6,77,000 5,61,201 5,00,636 21,876 10,83,713 83% 74%
Tamil Nadu 7,64,02,000 5,50,79,071 4,02,68,476 4,53,850 9,58,01,397 72% 53%
Telangana 3,77,25,000 3,05,36,661 2,48,69,323 3,49,660 5,57,55,644 81% 66%
Tripura 40,71,000 27,55,605 22,22,633 53,592 50,31,830 68% 55%
Uttar Pradesh 23,09,07,000 16,11,78,834 10,91,00,466 18,04,776 27,20,84,076 70% 47%
Uttarakhand 1,13,99,000 85,19,507 77,17,480 3,28,280 1,65,65,267 75% 68%
West Bengal 9,81,25,000 6,96,00,172 5,41,79,409 12,22,015 12,50,01,596 71% 55%
Miscellaneous 22,39,676 15,74,428 7,56,178 45,70,282
As of February 9, 2022 7:00 AM IST[189]

As of February 9, 2022, populations above the age of 15 are only eligible for vaccination. The percentage of population inoculated shown in the table above is according to the 2021 projected population of India with all age groups. According to the government, based on the projected mid-year count for 2021, the country's total population aged 15 years and above is approximately 101 crore. Around 93.99% of the 15+ population of the country have received at least one dose of the COVID-19 vaccine since the vaccination drive began. In addition to this, 73.13% of the eligible population has been fully vaccinated.[190]

Vaccine acceptance in India

Over 80% of the population of India have a positive response for getting anti covid shots. India has one of the lowest vaccine hesitancy in the world.[191] There was vaccine hesitancy in the initial months of 2021, especially in rural India and among poor and tribal populations. Constant government and public awareness drastically reduced vaccine hesitancy. Since May 2021, more than half of daily doses administered in India have been from rural parts.[192] Vaccine centers in India have witnessed large number of people willing to get covid vaccine resulting in overcrowding and mismanagement. Many centers across India in months of April & May reported severe shortage of covid vaccines due to large crowds turning up for vaccination. In cities like Mumbai, New Delhi, Bengaluru many people even after waiting for hours did not receive their covid vaccine due to shortage.[193] Since July, vaccine supply has drastically increased thus India is vaccinating at a very fast pace.[194]

One study published on vaccine acceptance shows that 79.5% of people from Delhi want to take a COVID-19 vaccine.[195] In another study which was published from West Bengal, a state in Eastern India, has shown that 77.27% of people want to take the COVID-19 vaccine.[196] According to the finding from these two studies, it can be expected that over 75% of people want to get a COVID-19 vaccine.

Vaccination by state

Arunachal Pradesh

As of July 2021, Arunachal Pradesh Government aims to inoculate 100 per cent of the state's population against COVID-19 by mid-August, chief minister Pema Khandu said. Due to hilly terrain, healthcare workers trekked mountains to administer doses to the rural population living in hills.As many as 7,91,371 doses of COVID-19 vaccines have been administered in Arunachal Pradesh so far, including 6,42,785 first doses and 1,48,586 second doses, according to the Union Health Ministry.[197]

Andhra Pradesh

Andhra Pradesh had received 370,000 doses of Covishield and 20,000 of Covaxin. It was decided that only Covishield would be administered. The state aims to vaccinate 32,000 people a day. However, on the first two days, only 61 and 47.8 per cent of those days' targets could be vaccinated. There were two cases of adverse events, but neither required hospitalization.[198] 7 out 13 districts in the state have administered more than 1 lakh doses.[199]

Note icon.svg As of 19 September

Sites conducting vaccination in AP
Emojione 1F3E5.svgVaccine - The Noun Project.svg

Total- 2,533
Government- 2,486
Private- 47

Source: CoWin Dashboard

Assam

Assam Chief Minister Himanta Biswa Sarma said the state has now become a Covid vaccine surplus state since it has administered vaccines to 5 lakh more people, against the total allocation by the centre. "Till August 19, the state has administered 1,51,73,826 doses of COVID-19 vaccines and out of these, the state has administered 1,21,59,162 doses of vaccines in the last 99 days. On average, the state has administered around 1.3lakh doses per day," Himanta Biswa Sarma said.Further the he has asked to keep a 24x7 vaccination system in some places in the state for the benefit of the people.[200] On the 9th month of the vaccination drive, Assam achieved a milestone of 2 crore vaccines administered in a single day.[201]

Bihar

Bihar received 569,000 doses of the vaccine. 4,64,160 health workers had registered for the vaccine, and the state expects to vaccinate 30,000 people a day across 300 sites. Some doctors had doubts about the efficacy of Covaxin and refused to take it.[202]

Chhattisgarh

Chhattisgarh government began vaccinations in the 18-44 age category, a mammoth effort given the sheer size of this age group and the national shortages in vaccine supply. The state government has also explained its decision to do away with slot booking for vaccinations (it currently conducts only walk-in operations) as a result of the fact that the poorest of the poor do not have good access to cellphones or the internet and therefore cannot use the Cowin app or website easily. Raigarh district of the state is different. An action plan enabled it to accomplish 100% first-dose vaccination of all eligible adults through meticulous planning and monitoring by field staff.

Delhi

Union Minister for Health & Family Welfare, Harsh Vardhan at a hospital in Shahdara, reviewing preparations for the vaccine program.
Health care workers administering the COVID-19 vaccination in New Delhi on 16 January 2021

4,319 health workers were administered the vaccine on the first day, and there were 51 minor and one major cases of adverse effects.[203] By day three, four people had been admitted to hospitals following complications, of which three had been later discharged.[24] The cumulative number of COVID-19 vaccine doses administered in the national capital so far is 1,37,85,457, including 39,41,416 second jabs.[204]

Goa

As of 24 September 2021 Goa has completely vaccinated 50% of its population .It had completed 100% coverage of first dose to all its eligible population on 10 September.[205]

Himachal Pradesh

Himachal Pradesh has become the first state to vaccinate all its adult population by at least one dose on 1 Sept 2021[206]

Karnataka

Karnataka Health Minister K. Sudhakar announced on 9 January that the state would be given 13.9 lakh (1.39 million) doses of Covishield in two batches. 6.3 lakh (630,000) health workers had registered for the vaccine.[207] Two people were admitted to hospital following complications; one person was later discharged.[24][208] The Health Minister has also set an target to completely vaccinate all adults by November end[209]

On 31 July, Karnataka became the first state in South India to cross the 3 crore doses mark [210] and in Bangalore, around 85% of the eligible population has been vaccinated with at least one shot, making the city the second highest after New Delhi.[211]

On 17 September Karnataka completed administering 5 crore doses along with administering around 30 lakh in a single day which is highest for any state[212]

Kerala

Kerala initially received 433,500 doses of Covishield, and an additional batch of 360,500 Covishield doses was announced three days later. In total, 459,853 people from the state registered for the vaccine, including 1,75,673 healthcare workers from state-run hospitals, 199,937 from private hospitals, 2,932 from federal hospitals, 74,711 police staff and 6,600 municipal workers. A total of 24,558 healthcare workers were vaccinated on the first three days. No adverse reactions were reported.[213] After vaccinating 3.75 lakh health workers by 11 February, the focus of the campaign shifted to other front-line staff such as police and municipal workers. The second dose was provided from 15 February onwards.[214]

COVID-19 Vaccination in Kerala. See or edit source data.

In order to create public confidence in the vaccine, several prominent officials and politicians took the vaccine. This includes Health Minister KK Shailaja,[215] Chief Minister Pinarayi Vijayan,[216] state police chief Lokanath Behera,[217] former Chief Minister VS Achuthanandan[218] and Thiruvananthapuram District Collector Navajoth Khosa.[217] By 21 February, 3,36,327 health workers and 57,658 other frontline staff had been vaccinated, and Kerala requested more vaccines from the national pool.[219]

Vaccination of senior citizens and people over 45 with pre-existing conditions began in March. In addition, vaccines are also provided to government employees involved in running the upcoming state elections. Since the online registration system was not accessible to everyone, particularly to senior citizens, vaccination was also provided without prior registration. Asha workers would help senior citizens in finding and booking slots at the nearest vaccination centre. District and Taluk hospitals and Primary Health Centres would provide vaccinations, in addition to selected private hospitals and special vaccination camps.[220]

Kerala was affected by the nationwide shortage of vaccines in mid-April, with stocks falling to 7.22 lakh doses. For example, in the Palakkad district, nearly half the camps were not in operational condition due to vaccine shortage. Vaccination centres were directed to use the remaining stocks to vaccinate front-line workers.[221] Vaccination of people in the 18-44 age group with certain medical conditions began in early May, and that of all people in the 40-44 age group began on June 4. These would be provided in public hospitals.[222]

By 16 Aug 2021, half of Kerala's estimated population of 35.4 million (and 61.98% of those over 18) had been vaccinated at least once.[223] By this point, 17,788,931 people had been vaccinated over a period of 213 days. In addition, 19% of the total population had been fully vaccinated.

Ladakh

On 11 July, it was reported that Ladakh had become the first union territory of India to have given the first dose to all of its eligible residents and "guest population" (hotel staff, migrant workers, and Nepalese citizens living in the territory).[224]

Madhya Pradesh

As of June 2, 2021. Madhya Pradesh vaccination has administered more than one crore vaccine doses. The pace of immunization has picked up, and more than 2.0 lakh doses are being administered daily.[225]

Due to a shortage of vaccines, the Madhya Pradesh health department has raised a tender estimated at Rs 50.0 Crores which will be open for bidding from 8 June to 22 June 2021.[226] Other States such as Karnataka have launched similar efforts which have garnered little success. In Cities, the government is making efforts to vaccinate the population by using drive-in vaccination centres.[227] Some government departments are pushing their own employees by bringing in policies such as No Vaccine, No Pay.[228]

In Rural Madhya Pradesh, Immunisation efforts have been marred by rumours and resistance by locals.[229][230]

Maharashtra

COVID-19 vaccination queue on May 1st 2021 in Nagpur

Maharashtra received 963,000 doses of Covishield and 20,000 doses of Covaxin. 785,000 health workers had registered to get the vaccination. 14,883 health workers in Maharashtra given COVID-19 vaccine on Tuesday[231] In Mumbai, only 1,926 people could be vaccinated on the first day due to a combination of low turnout and technical problems with the software. The vaccination drive was temporarily suspended due to the technical glitches in the software alerting people to their vaccination appointments.[26] As of September 2021, Maharashtra has administered 7,69,21,190 doses.[232]

Odisha

Odisha had received doses of both Covishield and Covaxin. The first vaccine dose was given to a sanitation worker on 16 January.[233] Covishield is the predominant vaccine used in Odisha. All the districts use Covishield to vaccinate their people. The only exception being Khurda where both covaxin and covishield are used to vaccinate people.[234]

Punjab

District Partilly vaccinated Fully vaccinated
Punjab 1,24,01,032 39,70,593
Amritsar 9,28,068 2,84,155
Barnala 2,37,966 62,623
Bathinda 4,79,590 1,32,592
Faridkot 2,64,436 85,861
Fatehgarh Sahib 2,79,410 71,600
Fazilka 3,27,953 74,740
Ferozepur 3,37,670 77,565
Gurdaspur 7,14,327 2,73,620
Hoshiarpur 9,04,010 3,58,254
Jalandhar 11,88,771 4,45,477
Kapurthala 3,62,368 1,20,103
Ludhiana 17,41,851 5,86,147
Mansa 2,58,334 54,240
Moga 3,92,514 99,182
Pathankot 3,85,532 1,40,325
Patiala 8,33,579 2,72,205
Rupnagar 3,28,678 99,171
Mohali 7,76,885 2,98,188
Sangrur 5,25,463 1,34,419
Shahid Bhagat Singh Nagar 3,32,143 1,15,504
Sri Muktsar Sahib 3,77,746 85,001
Tarn Taran 4,23,738 99,621
As of 2021-09-13
Sites conducting vaccination in Punjab
Emojione 1F3E5.svgVaccine - The Noun Project.svg

Total- 627
Government- 593
Private- 34

Source: CoWin Dashboard

Note icon.svg As of 15 September (13:30 IST)
OOjs UI icon alert-warning.svg This data is subject to change anytime.

Rajasthan

On 3 January 2021, the state conducted its first round of dry run for COVID vaccination in 7 districts.[235] On 13 January, Rajasthan received the first consignment of COVID-19 vaccines at Jaipur and Udaipur, which included Bharat Biotech's Covaxin and Serum Institute of India's Covishield.[236] The vaccines were then transported to state and district level storage centres.

On 16 January, as a part of the nationwide vaccination programme, the first vaccine dose was given to selected frontline health workers at 167 sites across the state.[237] In a review meeting held in January 2021 by the state government, the state head of World Health Organization said that Rajasthan is the best state in terms of preparation for COVID vaccination.[238] The second dose of the vaccine started from 15 February.[239]

By April 13, the state had administered 1 crore doses of vaccine.[240] On 14 April, a theft of 320 doses of Covaxin was reported from a government hospital in Jaipur.[241]

Since the central government did not agree to absorb vaccine costs, the state government announced free vaccines for the age group 18-45 from 1 May.[242][243] But the rollout was limited to 11 districts only due to shortage of vaccines.[244] Since May 10, every district in Rajasthan started opening slots for 18-45 age group.[245]

Uttar Pradesh

Uttar Pradesh was the first state to vaccinate over 20 lakh people.[246] Uttar Pradesh received 11,796,780 doses, it consumed 10,261,718 of them, and has 2,211,000 in the pipeline in April.[247]

As of September 2021, Uttar Pradesh is leading in the vaccination coverage with 9,88,83,207 doses administered in the state.[232]

On 25 September 2021 Uttar pradesh has completed administering 10 crore(100million) doses[citation needed]

Note icon.svg As of 22 September

Sites conducting vaccination in UP
Emojione 1F3E5.svgVaccine - The Noun Project.svg

Total- 4,699
Government[fn 1]- 4,600
Private[fn 2]- 99

Source: CoWin Dashboard

West Bengal

The third phase of vaccination commenced from 5 May 2021.[248] The state government had procured one lakh Covaxin doses and 3.5 lakh Covishield doses on its own for the phase 3 immunization.[249]

Adverse events

Like many other vaccinations, COVID-19 vaccines also have a risk of causing side effects. According to India's Union Ministry of Health and Family Welfare, the most common side-effects include pain or swelling at the injection site, fever, irritability and headaches.[250] The UK Government also lists fatigue, nausea and joint pain as common side-effects of the Oxford vaccine (known as Covishield in India).[251] Medical experts maintain that vaccines used are safe and their benefits outweigh the risks. It is also important to note that adverse cases do not necessarily have a causal relationship with the vaccines.[252]

A total of 617 serious adverse events were reported until March 29. Of these, 180 cases resulted in death. The Immunisation Technical Support Unit at the federal health ministry examined 192,000 case reports, including 12,400 deaths. In more than half of the examined cases of death, the cause of death was found to be acute coronary syndrome. However, the documentation had been completed for only 3,500 cases.[253]

By 7 June, 26,000 adverse events had been reported following immunisation. Of this, 24,901 were minor, 412 were significant and 887 were serious. 488 deaths were also reported, including 301 men and 178 women (details of 9 deaths were not available). Both vaccines had an adverse reaction rate of about 0.01% and a fatality rate of around 0.0001% - 24,703 events and 457 deaths from 210 million Covishield doses, 1,497 events and 20 deaths following 25 million Covaxin doses. Maharashtra reported the most adverse events (4,521), followed by Kerala (4,074), Karnataka (2,650) and West Bengal (1,456).[252][254]

On 15 June, the government published a review of case reports that had occurred between 5 February and 31 March 2021, focusing on 31 cases and one death from anaphylaxis that were believed to have been attributed to the vaccine, out of nearly 60 million doses administered in the time period. Only three of these cases, and the single death of a 68-year-old patient, were determined to be "vaccine-product related", with the remainder having been classified as coincidental, indeterminate, or unclassifiable. The report stated that "mere reporting of deaths and hospitalisations as serious adverse events does not automatically imply that the events were caused due to vaccines. Only properly conducted investigations and causality assessments can help in understanding if any causal relationship exists between the event and the vaccine."[255][256][257]

References

Footnote references

  1. ^ a b All government run vaccination centers provide free of cost vaccines
  2. ^ a b Vaccination Centres/facilities charge as per dose

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Notes

  1. ^ Moderna, Johnson & Johnson and Zydus Cadila are not yet under distribution
  2. ^ Zydus Cadila is the only vaccine to been approved for children above 12 years

External links