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The Lancet Gastroenterology and Hepatology

Latest series and commissions

FANATIC STUDIO / GARY WATERS / SCIENCE PHOTO LIBRARY

Alcohol-related liver disease

The Lancet Gastroenterology & Hepatology

Published: April 8, 2020

Excessive alcohol consumption is one of the leading causes of liver disease and the seventh leading cause of premature death worldwide. Alcohol-related liver diseases is now the leading cause of liver transplantation in the USA. In light of this burden, this Series examines alcohol-related liver disease from a number of angles, including diagnosis and outpatient management, current and future treatments for alcoholic hepatitis, and the place of liver transplantation in therapeutic strategies.

Creativa Images/Shutterstock

Viral hepatitis in children and adolescents

The Lancet Gastroenterology & Hepatology

Published: April 11, 2019

Since the launch of the global strategy to eliminate viral hepatitis as a public health threat by 2030, the predominant focus of efforts for hepatitis C has been on treating adults, and for hepatitis B, on improving preventive measures such as infant hepatitis B vaccination to halt new infections. Little attention has been given to treating children and adolescents living with chronic hepatitis C or hepatitis B. A pair of Series papers address the management of children and adolescents with chronic viral hepatitis infections, and identify policy and research gaps that must be addressed to improve care for this neglected population.

Romy Blümel

Liver diseases in the Asia-Pacific region: a Lancet Gastroenterology & Hepatology Commission

The Lancet Gastroenterology & Hepatology

Published: December 15, 2019

Almost two-thirds of global deaths due to liver disease in 2015 occurred in the Asia-Pacific region. This Commission examines the burden of liver diseases in the Asia-Pacific region, with an in-depth review of the epidemiology and aetiology of liver disease across 11 countries and territories. Although viral hepatitis remains the most common cause of liver disease in the region, the contribution of alcohol-related liver disease and non-alcoholic fatty liver disease is rapidly increasing. The Commission concludes with suggestions for priority areas for action to tackle changing landscape of liver diseases in the Asia-Pacific region.

Kevin Fales

Accelerating the elimination of viral hepatitis

The Lancet Gastroenterology & Hepatology

Published: January 8, 2019

Viral hepatitis is a major threat to public health and a leading cause of death worldwide. Each year, viral hepatitis kills 1.34 million people, which is comparable with deaths due to HIV/AIDS, malaria, and tuberculosis. With the advent of highly effective prevention measures and treatments, global elimination of viral hepatitis is a realistic goal; all WHO member states have committed to a global reduction in hepatitis-related deaths by 65% and new infections by 90% by 2030. This Commission sets out to appraise the current global situation and to identify priorities—for countries, regions, and globally—to accelerate efforts towards these ambitious targets.

Latest audio

(mp3, 7:04 mins, 6.48MB)

Colorectal cancer risk in patients with Crohn’s disease

Ola Olén discusses the assesment of colorectal cancer risk in patients with Crohn's disease.

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(mp3, 04:08 mins, 9.46MB)

Anti-TNFα therapy and risk of cancer in patients with immune-mediated diseases

Dr Akbar Waljee discusses findings from a cohort study investigating the risk of cancer recurrence or a new primary cancer in patients with IBD, rheumatoid arthritis, or psoriasis who received anti-TNFα therapy.

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(mp3, 07:21 mins, 16.8MB)

Liver damage in young adults

Dr Kushala Abeysekara discusses research looking at the prevalence of non-alcoholic fatty liver disease in young adults in England.

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(mp3, 08:20 mins, 19.0MB)

Treatments for IBS

Professor Alexander Ford discusses a meta analysis comparing different traditional treatments for irritable bowel syndrome.

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The Lancet Gastroenterology & HepatologyISSN 2468-1253